Our focus is on neurochemicals acting on the peripheral and central nervous system

We are enthusiastic about neurochemicals acting as agonists or antagonists on G-protein coupled receptors located in the peripheral and central nervous system. Our goal is to address the clinical needs to diagnose and treat the neurological pathologies at the origin of the disease; thus, avoiding a merely systematic treatment and rather stopping or delaying disease progression.

The chemical structure of small molecules is the key for successful drug design and development for both imaging probes and therapeutics. The combined, interdisciplinary knowledge of medicinal chemists, pharmacists and physicians allows drug adjustment and pave the way towards the application of our substances as tools for image-guided therapy.

The bottleneck of the drug development process is the preclinical screening of a compound library, as we still lack substantial methods for a fast and reliable biological assessment. We developed a complex dynamic 3D-cell culture method, which mimics the tissue situation and has the potential to fasten the screening process. Moreover, it conforms with the 3Rs (reduce, replace, refine) rule in animal ethics and will contribute to reduce the number of animals needed in drug testing.

Our main interests lie in

  • Inventive drug and tracer development of neurochemicals
  • Innovative drug screening methods
  • Interdisciplinary approaches close to medical application

EANM 2021 Plenary Lecture - Isotopes Past and Future

Missed the EANM 2021 plenary lecture on the availability of medicinal radioisotopes.

You can still watch it here.

CBmeds microONE promo video

For the SDG-3 presentation at the austrian parlament, our consortium of the FFG funded microONE project (CBmed, Univie, MUW, among others) produced a nice promo-video. Thank you to Thomas Wadsak for the nice production. (German only)

News and announcements

25.09.2024
 

Irem Duman successfully presented her work at the EUSAAT meeting for animal replacement research in Linz. We congratulate on her poster prize.

18.09.2024
 

Congratulations to Thomas Scheiblauer on finishing his excellent master thesis with the title "Design, synthesis, and characterization of GLP-1 receptor antagonists for imaging applications". We wish you all the best for your PhD in the group of Prof Thomas Mindt.

17.09.2024
 

Congratulations to Magdalena Wadsak on successfully completing her master’s degree! Her thesis, titled "Radiotracer development towards hepatic imaging" marks a significant achievement, showcasing her dedication and expertise. We are incredibly proud of her hard work and commitment.

10.09.2024
 

Verena Pichler was invited to discuss with the 17th district in Vienna on Microplastic and their impact on human health. The interaction with the public raises awareness and promotes innovative ideas for a healthier district.

09.09.2024
 

Magdalena took us on a journey to her passion besides radiochemistry, and we joined as a team one ballet session. Thank you for this exceptional experience.

15.08.2024
 

Ceren successfully finished her master thesis with the title "Optimization and Quality Assessment of Silk Fibroin Sponges for Scaffold-based 3D Cell Culture Model". We wish her all the best for her PhD and future carreer.