Our focus is on neurochemicals acting on the peripheral and central nervous system

We are enthusiastic about neurochemicals acting as agonists or antagonists on G-protein coupled receptors located in the peripheral and central nervous system. Our goal is to address the clinical needs to diagnose and treat the neurological pathologies at the origin of the disease; thus, avoiding a merely systematic treatment and rather stopping or delaying disease progression.

The chemical structure of small molecules is the key for successful drug design and development for both imaging probes and therapeutics. The combined, interdisciplinary knowledge of medicinal chemists, pharmacists and physicians allows drug adjustment and pave the way towards the application of our substances as tools for image-guided therapy.

The bottleneck of the drug development process is the preclinical screening of a compound library, as we still lack substantial methods for a fast and reliable biological assessment. We developed a complex dynamic 3D-cell culture method, which mimics the tissue situation and has the potential to fasten the screening process. Moreover, it conforms with the 3Rs (reduce, replace, refine) rule in animal ethics and will contribute to reduce the number of animals needed in drug testing.

Our main interests lie in

  • Inventive drug and tracer development of neurochemicals
  • Innovative drug screening methods
  • Interdisciplinary approaches close to medical application

EANM 2021 Plenary Lecture - Isotopes Past and Future

Missed the EANM 2021 plenary lecture on the availability of medicinal radioisotopes.

You can still watch it here.

CBmeds microONE promo video

For the SDG-3 presentation at the austrian parlament, our consortium of the FFG funded microONE project (CBmed, Univie, MUW, among others) produced a nice promo-video. Thank you to Thomas Wadsak for the nice production. (German only)

News and announcements

02.10.2023
 

The city of Vienna annually awards up to 13 grants in the following categories: architecture, visual arts, literature, music (composition), adult education, and science. These grants are given as recognition for outstanding overall achievements in the mentioned fields. Our PI Verena Pichler was now honored with this grand of the city of Vienna.

01.10.2023
 

Gratitude flows from our hearts to our Erasmus student Šachlevičiūtė Urtė from Lithuania (KIT) for sharing an incredible journey with us. Your presence has enriched our group, and the memories we've created together will forever be cherished. As you embark on new adventures, we wish you every success and fulfillment in the future.

18.09.2023
 

The PhaNuSpo doctoral school prepared an excellent programme for the PhD-students. Our group was excellently represented by Sarah, Irem, Verena and Lukas. An enormous success was the poster prize awarded to Verena on her poster on silk sterilization for biomedical purposes.

13.09.2023
 

Carolin successfully defended her master thesis "Investigation and derivatization of polystyrne micro- and nanoplastic particles for human health studies" at the faculty of chemistry. Congratulations to this enormous success and we wish you all the best for your career in science.

13.09.2023
 

Emily visited our lab to study micro- and nanoplastic via a FFG fundet school project during the summer holidays. It is always an honor to host such enthusiastic and curios young people.

27.07.2023
 

Congratulation to Karsten Bammingers first authorship published in pharmaceuticals with the title: On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach